24 packets (8 days supply)

Take 3 times a day with water or hot water before or between meals.

Adult daily dose of 3 sachets (1 sachet 1.5g) Yokukansankachimpihange Extract Powder...2,300mg
[Extracted from 1.5g each of Japanese Angelica Root, Cnidium Rhizome, Citrus Unshiu Peel, and Uncaria Hook, 2.0g each of Atractylodes Lancea Rhizome and Poria Sclerotium, 2.5g of Pinellia Tuber, 1.0g of Bupleurum Root, and 0.75g of Licorice. ]
Contains hydroxypropyl cellulose and lactose as additives.

Detailed Explanation of Ingredients and Effects):

Soushutsu (Atractylodes lancea):Primarily used to address abnormalities in moisture metabolism. Therefore, it is effective in treating frequent urination, polyuria, or difficulty in urination.

Bukuryo (Poria Sclerotium):A type of fungus used in traditional Chinese herbal medicine. It is mainly employed to regulate moisture metabolism and has the effect of eliminating excess moisture from the body. Additionally, it assists the function of the spleen, helping to balance the digestive system.

Senkyu (Cnidium Rhizome):A plant belonging to the Umbelliferae family, it promotes blood circulation and improves blood circulation. It is also used to alleviate symptoms such as headaches and irregular menstruation.

Choutoukou (Uncaria Hook):A plant in the grass family, it is believed to have anti-inflammatory effects and is used to relieve symptoms of colds and joint pain. It is also used to alleviate pain in joints and muscles.

Toki (Japanese Angelica Root):A plant in the Apiaceae family, often used in traditional Chinese medicine, particularly for women's health issues. It primarily promotes blood circulation and improves blood flow, making it useful for alleviating irregular menstruation and menstrual pain.

Saiko (Bupleurum Root):Primarily used to treat symptoms of fullness and discomfort in the upper abdomen, from the epigastrium to the costal region. It addresses symptoms of resistance, tenderness, and pain.

Kanzo (Licorice):Contains sweet-tasting components such as glycyrrhizinic acid and substances that inhibit carbohydrase. It is also said to have anti-inflammatory and antiviral effects.

As a guideline for moderate physical strength, those with a slightly weak digestive system, nervousness, easy anger, irritability, etc., have the following symptoms: neurosis, insomnia, crying at night in children, pedophilia (irritability), menopause, Blood Path Disorder, Teeth Grinding (Note) "Blood Path Disorder'' refers to psychoneurological symptoms and physical symptoms such as mental anxiety and irritability that occur with changes in women's hormones such as menstruation, pregnancy, childbirth, postpartum, and menopause.

It is said to be effective for symptoms such as stress, irritation, anxiety, headaches, and stiff shoulders. It mainly aims to improve stress symptoms by regulating liver qi and improving stagnation of qi, and by balancing the mind and body.

In recent years, the Japanese herbal medicine yokukansan has been used in Japan as a treatment for dementia. For thousands of years, yokukansan has been utilized to control night terrors in children and manage restlessness and aggression in children. In 2010, the Japanese Society of Neurology recommended yokukansan for managing dementia symptoms.

Researchers explored the potential of yokukansan's active components to cross the blood-brain barrier in animal trials. Overcoming the challenge of delivering medicines to the brain, the study used chromatography, as discussed in the article "Online Solid Phase Extraction and LC/MS Analysis of Thyroid Hormones in Human Serum." The findings suggest the feasibility of delivering ingredients into the brain, offering potential benefits for dementia treatment.

Insomnia: Acts on the autonomic nervous system to calm heightened nervousness, mental anxiety, and tension.

Teeth grinding (bruxism): Acts on the autonomic nervous system to relax muscle tension and alleviate symptoms.

Childhood night crying: Considered effective for intense, high-pitched crying at night. It is sometimes administered to both the child and the mother simultaneously, as the cause of a child's night crying is often attributed to the mother's anxiety and irritability.

Dementia: Individuals with dementia often experience peripheral symptoms such as anxiety, insomnia, depression, excitement, wandering, and delusions alongside the main symptoms of dementia. Yokukansan is said to be effective for these peripheral symptoms and is commonly used.

**During pregnancy or breastfeeding, be sure to consult with a physician.**

Given that licorice is included as an ingredient, closely monitor serum potassium levels, blood pressure, etc., and discontinue use if any abnormalities arise. 

**When concurrently using other herbal formulations or medications, be cautious of ingredient overlap.**

**Serious Side Effects:**

Serious side effects may include interstitial pneumonia, pseudoaldosteronism, heart failure, myopathy, rhabdomyolysis, liver dysfunction, and jaundice.

**If unusual symptoms occur, such as fever, difficulty breathing, elevated blood pressure, swelling, fatigue, or sudden weakness, discontinue use and consult a physician.**

This translation is provided for informational purposes, and it is crucial to seek advice from a healthcare professional for accurate and personalized guidance.